Authors

Mozaffarian D, Katan MB, Ascherio A, Stampfer MJ, Willett WC.

Title

Trans fatty acids and cardiovascular disease.

Full source N Engl J Med. 2006 Apr 13;354(15):1601-13


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Abstract

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings:

Trans fats, unsaturated fatty acids with at least one double bond in the trans configuration (Figure 1), are formed during the partial hydrogenation of vegetable oils, a process that converts vegetable oils into semisolid fats for use in margarines, commercial cooking, and manufacturing processes. From the perspective of the food industry, partially hydrogenated vegetable oils are attractive because of their long shelf life, their stability during deep-frying, and their semisolidity, which can be customized to enhance the palatability of baked goods and sweets. The average consumption of industrially produced trans fatty acids in the United States is 2 to 3 percent of total calories consumed. [...]

Physiological Effects of Trans Fatty Acids
Serum Lipids
Systemic Inflammation
Endothelial-Cell Function
Other Effects
Potential Molecular Mechanisms
Intake of Trans Fat and Cardiovascular Disease
CHD
Sudden Death from Cardiac Causes
Diabetes
Trans Fatty Acids from Ruminants
Reducing Intake of Trans Fatty Acids
Optimal Levels
Consumers' Choices

Industry Alternatives
Potential Benefits of Reducing Intake
Conclusions